DCA (DICHLOROACETATE)
FREQUENTLY ASKED
QUESTIONS
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Letter from Dr. Evangelos Michelakis
October 2008
Dear Friends,
This is a short update on our DCA project at the University of
Alberta.
We would like to express our gratitude and
appreciation for your support in our fund raising efforts. Through
donations on this web page and philanthropic foundations we have
been able to expand our basic science efforts as well as initiated
and run two clinical trials in Edmonton. In collaboration with the
Cross Cancer Institute and the Alberta Cancer Board, we are running
clinical trials in patients with solid tumours that have failed
standard therapies as well as in patients with malignant brain
tumours. The objectives of these trials are to determine the safety
of DCA as a novel therapy for cancer. We are trying to determine the
optimal dose and to monitor potential adverse effects, such as drug
interactions and toxicities. This is necessary to do before
embarking on more definitive trials to test the effectiveness of
this drug in the treatment of cancer. We have enrolled more than
half of our target numbers of patients in these trials and we are
gaining invaluable experience. Both the progress and the preliminary
results are promising, although the detailed outcomes of these
trials will be published in medical journals, after their
completion.
We are very encouraged by these early results, and are now
preparing to initiate additional clinical trials, in Edmonton and in
collaboration with other Universities in around the world.
We are gratified to see that other researchers have begun to
share our excitement with DCA. Several recent studies have reported
findings similar to ours. These include some work suggesting that
DCA has anti-cancer effects in endometrial and prostate cancer (see
the references at the end of this letter). However a word of
caution, these experiments were not done in patients, but rather in
animals and test tubes, and so the applicability of these results to
human disease has not been determined. They make however, the need
for clinical trials even more pressing. We also reiterate that in
the absence of knowledge about the safety and effectiveness of this
drug in people it is unwise to be taking this agent unsupervised and
outside of a clinical trial.
On behalf of the many
people here at the University of Alberta that continue to work on
DCA,
Thank you very much!
Recent medical reports on DCA:
Journal: Gynecol Oncol. 2008 Jun;109(3):394-402
Title:
Dichloroacetate induces apoptosis in endometrial cancer
cells.
Authors: Wong JY, Huggins GS, Debidda M, Munshi NC, De
Vivo I. Channing Laboratory, Department of Medicine, Brigham and
Women's Hospital and Harvard Medical School, Boston, Massachusetts
02115, USA
Journal : Prostate. 2008 Aug 1;68(11):1223-3
Title:
Dichloroacetate (DCA) sensitizes both wild-type and over expressing
Bcl-2 prostate cancer cells in vitro to radiation.
Authors: Cao
W, Yacoub S, Shiverick KT, Namiki K, Sakai Y, Porvasnik S, Urbanek
C, Rosser CJ. Department of Urology, University of Florida,
Gainesville, Florida, USA
Journal: Proceedings of the National Academy of Sciences, PNAS
2007 104:9445-9450
Title: Metabolic targeting of hypoxia and HIF1
in solid tumors can enhance cytotoxic chemotherapy
Authors: Rob
A. Cairns, Ioanna Papandreou, Patrick D. Sutphin, and Nicholas C.
Denko Stanford University, Palo Alto, CA, USA
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Q:What is DCA and how
does it work?
Q:Can my doctor order DCA?
Q:Can I find and use
DCA on my own?
Q:Can DCA treat my cancer?
Q:When will the
clinical trials start?
Q:How can I help?
Q:How can I make a
donation?
Q:Is there more information I can
read?
Q:How is the
fundraising going?
Q:I missed Mody's interview with Doctor
Michelakis. Is there any way I can listen to it?
Q:I missed Mody's
most recent interview (mid-September) with Doctor Michelakis. Is
there any way I can listen to it?
DCAuction Frequently Asked
Questions:
Q:How did the
DCAuction on the Dirt Bike turn out?
Q: How did the
DCAuction on the YL Country sign and the TELUS COUNTRY FEVER V.I.P
package turn out?
Q:How did the DCAuction on the Millennium Project
Quilt turn out?
Q: How did the DCAuction on the A&W Block
Party turn out?
Q: How did the DCAuction on the IGA/Wild Rose
Guest Ranch Catered BBQ package turn out?
Q: How did the
DCAuction on the Ultra Helicopter Tour and overnight stay at the
Peace Valley Guest Ranch package turn out?
Q:How did the
DCAuction on the Bunch of Bison turn out?
Q:How did the
DCAuction on the Gravel and V.I.P. Movie Pass turn out?
Q:How did the DCAuction on the Entertainment
Package and Power Bleaching turn out?
Q:How did the
DCAuction on the Autographed Snowbird Print and Tim Horton's
VIP Donut Coffee Package turn out?
Q:How did the
DCAuction on the Sawridge Inn Party for 20 and 2 Minute Coop
Shopping Spree/Eastern Star Bison Package turn out?
Q: How did the
DCAuction on the Hockey Cards and the NAIT Voucher turn
out?
Q: How did
the DCAuction on the Basement Digging, Deep Well
System and Storm Tickets turn out?
Q: How did the DCAuction
on the Basement Digging, Electrical Service and Satey Package
turn out?
Q:
How did the DCAuction on the Signature Washburn Guitar turn
out?
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Q:
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How did the
DCAuction on the Dirt Bike turn out?
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A: |
It's an 80 CC MFC (Motorized Fun Company)
dirt bike. 3 speeds. Great for the kids.
The
donation was courtesy of Complete
Details in Peace River .
Bidding
closed Noon on May 25th with all money raised going towards research
into the generic drug, DCA. Research will be conducted at the
University of Alberta.
Congratulations to Peace Country Films who made the
highest bid of $1000.
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DCAuction
It's an 80
CC MFC (Motorized Fun Company) dirt bike. 3 speeds. Great for
the kids.
The donation is courtesy of
Complete Details in
Peace River.
Bidding closed
at Noon on May 25th.
All
money raised goes towards research into the generic drug, DCA,
being conducted at the University of Alberta.
Congratulations
and many thanks to
Peace Country Films
who made the top bid on the bike.
TOP BID :$ 1,000
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Q:
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How did
the DCAuction on the YL Country sign and the TELUS COUNTRY FEVER
V.I.P. package turn out?
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A: |
Up for bid was the YL Country sign that hung
on the side of the building for ten years; also as part of our
"Heritage" package was Two reserved seating Weekend passes to Telus
Country Fever at Evergreen Park in Grande Prairie, June 29th till
July 1st. The premium ticket package and VIP camping pass is worth
$500.00 and the sign is priceless. Bidding ended at Noon on
Friday June 1st. All money raised goes towards DCA research.
Congratulations to
Joan Setz who made the highest
bid of $275 .
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DCAuction
It's a
piece of HISTORY...
The YL Country sign .
It's HISTORY in the making...
a V.I.P.
Camping Pass &
2 Reserved Seat
Tickets to
TELUS COUNTRY
FEVER .
Bidding closed
at Noon on June 1st.
All
money raised goes towards research into the generic drug, DCA,
being conducted at the University of Alberta.
Congratulations
and many thanks to
Joan Setz
who made the top bid on the package.
TOP BID : $ 275
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Q:
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How did the
DCAuction on the Millennium Project Quilt turn out?
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A: |
A Queen sized Millennium project Quilt
donated by Caribou
Cresting.
There are over a
million stitches of embroidery and features an Alberta wildlife
design. Bidding closed at noon on June 15th. All money raised
goes towards DCA research.
Congratulations to Roberta Hawryluk of Black Gold
Drilling who made the highest bid of $900 .
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DCAuction
A Queen
sized Millennium project Quilt donated by Caribou Cresting.
There are over a million stitches of
embroidery and features an Alberta wildlife design - with
artist signature.
Bidding closed
at Noon on June 15th.
All
money raised goes towards research into the generic drug, DCA,
being conducted at the University of Alberta.
Congratulations
and many thanks to
Roberta Hawryluk
who made the top bid on the quilt.
TOP BID : $ 900
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Q:
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How did the
DCAuction on the A&W Block Party turn out?
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A: |
A Chubby Chicken Block Party for you and 40
of your friends. Courtesy of the Peace
River A&W.
Delicious Chubby
Chicken, A&W legendary root beer, salads, fries... all the
fixins. Catered by A&W and YL Country & KIX. Bidding
closed at noon on June 29th. All money raised goes towards DCA
research.
Congratulations to Cindy of Best Truck Service who made
the highest bid of $400 .
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DCAuction
A Chubby
Chicken Block Party
for you and 40 of
your friends.
Courtesy of the Peace River A&W.
Delicious Chubby Chicken, A&W
legendary root beer, salads, fries... all the fixins.
Catered by A&W and YL Country &
KIX.
Bidding closed at Noon on June 29th.
All money raised goes towards
research into the generic drug, DCA, being conducted at the
University of Alberta.
Congratulations and many thanks to
Cindy from
Best Truck Service
who made
the top bid on the block party.
TOP
BID : $ 400
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Q:
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How did the
DCAuction on the IGA/Wild Rose Guest Ranch Catered BBQ package turn
out?
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A: |
A wonderful catered Barbeque courtesy of the
IGA Supercenter. Enough food -
including marinated rib-eye steaks - for 20 people, served at the
beautiful Wild Rose Guest
Ranch. This auction item also includes an overnight stay at
the Wild Rose Guest Ranch
nestled in the Peace River Valley. Bidding closed at noon on
July 13th . All money raised
goes towards DCA research.
Congratulations to United Carpet of Peace River who made
the highest bid of $1,900 .
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DCAuction
A wonderful
catered Barbeque
courtesy of the
IGA Supercenter.
Enough food - including marinated rib-eye
steaks - for 20 people, served at the beautiful Wild Rose Guest Ranch.
This auction item also includes an
overnight stay at the Wild Rose
Guest Ranch nestled in the Peace River Valley.
Bidding closed at Noon on July 13th.
All money raised goes towards
research into the generic drug, DCA, being conducted at the
University of Alberta.
Congratulations and many thanks to
United
Carpet of Peace River
who
made the top bid on the BBQ party.
TOP BID :
$
1,900
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Q:
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How did the
DCAuction on the Ultra-Helicopter with an overnight stay at the
Peace Valley Guest Ranch package turn out?
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A: |
Experience the colours of the Peace River
Valley from the earth and the sky with an Ultra Helicopter Tour with an
overnight stay at the Peace Valley
Guest Ranch.
When you land, hop on the back of a horse for a
trail ride, then settle down for a home cooked meal. Afterwards,
retire for a quiet evening nestled in the bosom of the North's
natural surroundings. Wake up to a one of a kind sunrise and
breakfast, before boarding the helicopter home.
Bidding closed at noon
on July 13th . All money
raised goes towards DCA research.
Congratulations to Ramona Thoma of Nomad Electrical
Contractors Ltd. who made the highest bid of $1,000.
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DCAuction
Experience
the colours of the Peace River Valley from the earth and the
sky. Ultra Helicopter
Tour with an overnight stay at the Peace Valley Guest Ranch.
When you land, hop on the back of a horse
for a trail ride, then settle down for a home cooked meal.
Afterwards, retire for a quiet evening nestled in the bosom of
the North's natural surroundings. Wake up to a one of a kind
sunrise and breakfast, before boarding the helicopter home.
Bidding closed at Noon on July
27th.
All money raised goes
towards research into the generic drug, DCA, being conducted
at the University of Alberta.
Congratulations and many thanks to
Ramona Thoma
of Nomad Electrical Contractors Ltd. who made the top
bid on the Heli-Tour package.
TOP
BID : $ 1,000
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Q:
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How did the
DCAuction on the Bunch of Bison turn out?
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A: |
The 'Bunch of
Bison' online auction for DCA.
The Majestic Bison
Ranch just outside of Peace River is donating a 600 pound bison , cut and wrapped for you by
Johnny's Sausage and Abatoire.
Ready your freezer for approximately $1000 worth of Premium
Alberta Bison !
Bidding closed at noon on August 10th . All money raised goes
towards DCA research.
Congratulations to Marsha of Tanne Appliances who made the highest
bid of $1,380.
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DCAuction
The Bunch of Bison online auction
for DCA. The Majestic Bison
Ranch just outside of Peace River is donating a
600 pound
bison , cut and wrapped for you
by Johnny's Sausage and
Abatoire.
Bidding closed at Noon
on August 10th.
All
money raised goes towards research into the generic drug, DCA,
being conducted at the University of Alberta.
Congratulations
and many thanks to
Marsha of Tanne Appliances who
made the top bid on the Bunch of Bison.
TOP BID :
$ 1380
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Q:
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How did the
DCAuction on the Gravel and V.I.P. Movie Pass turn out?
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A: |
TWO
ITEMS go on the DCA auction block this time . . .
#1 : If you want to re-do your
driveway, fill in nasty pot holes, redesign your backyard, paths or
deck, then this item really 'rocks' and it's just a 'stone's throw
away'...
Weberville Aggregate Sand and Gravel
Sales has donated 525 YARDS of
GRAVEL (3 inch minus), valued at $5,000 !!! (Does not include
delivery.)
#2 : See all the movies on the big
screen with a guest for an entire year...
Now's your chance to enjoy special treatment
with the Cinema 72 V.I.P. Movie
Pass, valued at over
$1200.
Bidding closed at noon August 24th on both items. All money
raised goes towards DCA research.
Congratulations to Brett Meston who made the highest bid
of $4,850 on item #1.
Congratulations to Belle Marketing who made the highest
bid of $650 on item #2.
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DCAuction
#1:Weberville Aggregate Sand and Gravel
Sales has donated 525
YARDS of GRAVEL (3 inch minus), valued at $5,000 !!! (Does not include
delivery.)
#2:
Take a guest and see all the latest movies on the big screen
for an entire year...
Now's your
chance to enjoy special treatment with the Cinema 72 V.I.P. Movie Pass,
valued at over $1200.
Bidding closed at Noon on August 24th.
All money raised goes towards
research into the generic drug, DCA, being conducted at the
University of Alberta.
Congratulations and many thanks to
Brett
Meston who made the top bid on the Gravel.
TOP BID
#1: $ 4,850
Congratulations and many thanks to
Belle
Marketing who made the top bid on the V.I.P. Movie
Pass.
TOP
BID #2: $
650
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Q:
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How
did the DCAuction on the Entertainment Package and the
Power Bleaching turn out?
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A: |
TWO
ITEMS go on the DCA auction block this time . . .
#1 : A tremendous entertainment
package...
Two
floor seats to the Blueman
Group in Grande Prairie on September 25th.
PLUS...Two tickets to the final four performances of the Canadian Finals Rodeo November
7th-11th in Edmonton including two
nights accommodations .
PLUS...$200 worth of gas vouchers to help you
get to these outstanding events....
This
Entertainment Package is valued at more than $1000.00
#2 : Have a Whiter, Brighter
Smile...
Doctor
Winston Wing of Wing Dental
Center has donated a Power
Bleaching worth $1000.
This
procedure is the most effective way to whiten your teeth,
hassle-free and in just three hours you'll have a brand new smile
from Wing Dental Center.
Bidding on both items closed at noon on September 7th . All money raised goes
towards DCA research.
Congratulations to Laurie Girrard who made the highest
bid of $950 on item #1.
Congratulations to Judy Kjemhus who made the highest bid
of $1,050 on item #2.
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DCAuction
#1: A tremendous
entertainment package...
Two floor seats to the Blueman Group in Grande
Prairie on September 25th.
PLUS...Two tickets to the final four performances of the
Canadian Finals Rodeo
November 7th-11th in Edmonton including two nights accommodations .
PLUS...$200 worth of gas vouchers to
help you get to these outstanding events....
This Entertainment Package is valued at
more than $1000.00
#2: Have a Whiter, Brighter
Smile...
Doctor Winston Wing of Wing Dental Center has donated
a Power Bleaching
worth $1000.
This procedure is the most effective way
to whiten your teeth, hassle-free and in just three hours
you'll have a brand new smile from Wing Dental Center.
Bidding closed Noon
on September 7th.
All
money raised goes towards research into the generic drug, DCA,
being conducted at the University of Alberta.
Congratulations
and many thanks to
Laurie Girrard who made the top
bid on the Entertainment Package.
TOP BID
#1: $ 950
Congratulations and many thanks to
Judy
Kjemhus who made the top bid on the Power
Bleaching.
TOP
BID #2: $
1,050
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Q:
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How
did the DCAuction on the Autographed Snowbirds Print and
the Tim Horton's Donut Coffee Auction turn out?
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A: |
TWO
ITEMS go up on the DCA auction block this time around
as well . . .
#1 :
Bring back memories of the 2007 Air Show...
A beautiful 2007 Framed Print of the Canadian Snowbirds that has been
autographed by all the pilots.
Send your bid in to get this priceless print and memory on your wall.
#2 : DCA
for D.C.A. from Tim Horton's...
It's the
Donut Coffee Auction for DCA. Tim Horton's has donated 2 Coffees and 2 Donuts every day for a year !! Get the
V.I.P treatment at Tim Horton's by being the top bidder.
Bidding on both
items closed noon
September 21st . All money
raised goes towards DCA research.
Congratulations to Daryl Presakarchuk who made the
highest bid of $210 on item
#1.
Congratulations to Susan Jonk who made the highest bid of
$405 on item #2.
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DCAuction
#1: Bring back memories
of the 2007 Air Show...
A
beautiful 2007 Framed
Print of the Canadian Snowbirds that has been
autographed by all the
pilots.
#2:
DCA for D.C.A. from Tim Horton's...
It's the Donut Coffee Auction for DCA. Tim Horton's has donated 2 Coffees and 2 Donuts every day for a year !! Get
the V.I.P treatment at Tim Horton's.
Bidding closed Noon September
21st.
All money raised goes
towards research into the generic drug, DCA, being conducted
at the University of Alberta.
Congratulations and many thanks to
Daryl
Presakarchuk who made the top bid on the Autographed
Snowbird Print.
TOP BID #1: $
210
Congratulations
and many thanks to
Susan Jonk who made the top
bid on the Tim Horton's VIP Donut Coffee Package.
TOP BID
#2: $
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Q:
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How did the DCAuction on the Sawridge Inn
Party for 20 and 2 Minute Coop Shopping Spree/Eastern Star Bison
Package turn out?
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A: |
ANOTHER DOUBLE
DCA AUCTION this time around . . .
#1 : Make your next big party the
BIGGEST EVER...
Here's your chance for a
FULL Evening OUT at the
Peace River Sawridge Inn...
A 5 COURSE
MEAL & SAWRIDGE
WINE for 20 of your
friends PLUS...
Free POOL in Sharks after dinner
PLUS...
A Door
Prize draw for an evening in the President's Suite with
Champaigne
#2 : Feel like the store is
yours PLUS take home a whole adult Bison (cut
& wrapped)...
It's a TWO MINUTE SHOPPING SPREE up to
$1500 at the Peace River CO-OP PLUS...
A WHOLE ADULT
BISON from Eastern Star
Bison , cut and wrapped.
Bidding on both items closed at noon on October 5th . All money raised goes
towards DCA research.
Congratulations to Brian Reading who made the highest bid
of $1,800 on item #1.
Congratulations to Tara Harbaruk who made the highest bid
of $1,000 on item #2.
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DCAuction
#1: Make your next big
party the BIGGEST EVER...
Here's your
chance for a FULL Evening
OUT at the Peace River
Sawridge Inn...
A 5 COURSE MEAL & SAWRIDGE WINE for 20 of your friends PLUS...
Free
POOL in Sharks after dinner PLUS...
A Door
Prize draw for an evening in the President's Suite
with Champaigne.
#2:
Feel like the store is yours PLUS take home a
whole adult Bison (cut & wrapped)...
It's a TWO
MINUTE SHOPPING SPREE up to $1500 at the Peace River CO-OP PLUS...
A WHOLE
ADULT BISON from Eastern
Star Bison (cut and wrapped).
Bidding closed at Noon on October
5th.
All money raised goes
towards research into the generic drug, DCA, being conducted
at the University of Alberta.
Congratulations and many thanks to
Brian
Reading who made the top bid on the Sawridge
Party Package for 20.
TOP BID #1: $
1,800
Congratulations
and many thanks to
Tara Harbaruk who made the
top bid on the Shopping Spree/Bison Package.
TOP BID
#2: $
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Q:
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How did the
DCAuction on the Hockey Cards and NAIT Voucher turn out?
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A: |
IT WAS
A TRIPLE DCA AUCTION . . .
#1 : Hockey Fans REJOICE...
A FRAMED ORIGINAL
SET of 05/06 SEASON MCDONALD'S UPPER DECK ICE HEROES HOCKEY
CARDS!!! You'll get all your favourite players like Mario
Lemieux, Martin Bodeur, Jason Smith, and many more. (Valued at
approximately $1,000.)
#2 :
Hockey Fans REJOICE FURTHER YET...
A FRAMED ORIGINAL SUBSET of 05/06 SEASON
MCDONALD'S UPPER DECK ICE HEROES HOCKEY CARDS!!! You'll get
all your favourite players like Wayne Gretsky, Joe Sakic, Steve
Yzerman and many more. (Valued at approximately $1,000.)
#3 : Prepare for success and get
educated for the real world...
NAIT (Northern Alberta Institute of
Technology) has donated a $1,000 VOUCHER TOWARDS TUITION this
coming winter term at any NAIT NORTHERN
CAMPUS !!!
Bidding on all items closed at
noon on October 19th . All money raised goes
towards DCA research.
Congratulations to Caribou Cresting who made the
highest bid of $900 on item
#1.
Congratulations to Caribou Cresting who made the
highest bid of $900 on item
#2.
Congratulations to Nancy Smith who made the highest
bid of $800 on item #3.
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DCAuction
#1: Hockey Fans
REJOICE...
A FRAMED ORIGINAL SET of 05/06 SEASON
MCDONALD'S UPPER DECK ICE HEROES HOCKEY CARDS!!!
#2: Hockey Fans REJOICE FURTHER
YET...
A FRAMED ORIGINAL SUBSET of 05/06 SEASON
MCDONALD'S UPPER DECK ICE HEROES HOCKEY CARDS!!!
#3 : Prepare for success and get
educated for the real world...
NAIT (Northern Alberta Institute of
Technology) has donated a $1,000 VOUCHER TOWARDS TUITION
this coming winter term at any NAIT NORTHERN CAMPUS !!!
Bidding closed at Noon on October
19th.
All money raised goes
towards research into the generic drug, DCA, being conducted
at the University of Alberta.
Congratulations and many thanks to
Caribou
Cresting who made the top bid on the Hockey
Cards Main set.
TOP BID #1: $
900
Congratulations
and many thanks to
Caribou Cresting who made
the top bid on the Hockey Cards Sub-set.
TOP BID
#2: $
900
Congratulations
and many thanks to
Nancy Smith who made the
top bid on the Nait Voucher.
TOP BID #1: $
800
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Q:
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How did the
DCAuction for the basement, deep well system and storm tickets turn
out?
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A: |
IT WAS ANOTHER
TRIPLE . . .
#1 :
Digging of a Basement...
If you are
contemplating a new home in the Grimshaw/Peace River area, Dalyn Contracting will dig your basement for you.
This item is
valued at $1,500 !!!
#2 : Deep
Well Pump System...
NorAlta Rewind and DCA bring you
a Brand New Deep Pump System
A 230 volt 4 inch submersible pump, a
half HP 230 volt control box, a 35 gallon pressure tank, pump
cable, drop pipe and a 1" X 10" tank tee kit. THE WORKS!!!
(installation not included)
This package has a retail value of $2,000
!!!
#3 :
Catch the Storm, EVERY TIME...
T. T. Oilfield Services in Mayerthorpe has
donated 30 GAME PASSES to any of the Grande Prairie Storm Regular season
home games. You'll never miss the game, or you and your friends
will be able to enjoy the games in good company because these
tickets are good for all the Storm home-game action.
Bidding on all items closed at noon on November 2nd. All money raised goes
towards DCA research.
Congratulations to Greg & Robin
Berreth of Circle B
Ventures who made the highest bid of $1,100 on item #1.
Congratulations to Keith of Northern Digital Services who
made the highest bid of $1,000
on item #2.
Congratulations
to Ian McGillis who
made the highest bid of $310
on item #3.
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DCAuction
#1: Digging of a
Basement...
If you are contemplating a
new home in the Grimshaw/Peace River area,
Dalyn
Contracting will dig
your basement for you.
This item is
valued at $1,500 !!!
#2:
Deep Well Pump System...
NorAlta
Rewind and DCA bring you a
Brand New Deep Pump Sysytem
230 volt 4 inch submersible
pump
Half HP 230 volt control box
35 gallon pressure tank
pump cable
drop
pipe
1X10 inch tank tee kit
(installation not included)
This package
has a retail value of $2,000 !!!
#3 : Catch The Storm, EVERY
TIME...
T. T.
Oilfield Services in Mayerthorpe has donated
30 GAME
PASSES to any of the Grande
Prairie Storm Regular season home games.
You'll never miss the game, or you
and your friends will be able to enjoy the games in good
company because these tickets are good for all the Storm
home-game action.
Bidding closeds
at Noon, November 2nd.
All money raised goes towards
research into the generic drug, DCA, being conducted at the
University of Alberta.
Congratulations and many thanks to
Greg &
Robin Berreth of Circle B Ventures who made
the top bid on the digging of a basement.
TOP BID
#1: $ 1,100
Congratulations and many thanks to
Keith of Northern Digital
Services who made the top bid on the deep well
system.
TOP
BID #2: $
1,000
Congratulations
and many thanks to
Ian McGillis who made the
top bid on the Storm tickets.
TOP BID #1: $
310
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Q:
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How did the
DCAuction on the Basement Digging, Electrical Srevice and
Safety Package turn out?
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A: |
IT WAS ANOTHER
TRIPLE DCA AUCTION . . .
#1 :
Digging it up for DCA...
Dave Mobile Tire has donated the
labour for Dalyn
Contracting to dig your
basement. If you're planning on a new home, throw DCA, Dave
Mobile Tire and Dalyn Contracting in the mix.
#2 : This
item is ELECTRIFYING...
J-Wire Electric Ltd. has donated
$1,000 worth of electrical
work, which includes labour and parts. (Does not include
fixtures.)
#3 : Keep it safe...
Keep it safe with Peace Safety and
Environmental Training and DCA. Up for bids is a Safety Package
for the woodsman. Get chainsaw
protective pants, ear
protection, helmet,
safety eyewear, an axe and a chainsaw from Rentco. This safety package is valued
at approximately $600.
Bidding on all items closed at noon on November 16th. All money raised goes
towards DCA research.
Congratulations to Julie Gagnon who made the highest
bid of $1,250 on item #1.
Congratulations to Karen Stephens who made the highest bid of
$550 on item #2.
Congratulations to Jack Hanson who made the highest
bid of $650 on item #3.
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DCAuction
#1: Digging it up for
DCA...
Dave Mobile Tire has donated the
labour for Dalyn
Contracting to dig your
basement. If you're planning on a new home, throw
DCA, Dave Mobile Tire and Dalyn Contracting in the
mix.
#2: This item is
ELECTRIFYING...
J-Wire Electric Ltd. has
donated $1,000 worth of
electrical work, which includes labour and parts.
(Does not include fixtures.)
#3 : Keep it safe...
Keep it safe with Peace Safety and
Environmental Training and DCA. Up for bids is a Safety
Package for the woodsman. Get chainsaw protective pants,
ear protection, helmet, safety eyewear, an axe and a chainsaw from Rentco.
This safety package is valued at
approximately $600.
Bidding
closed at Noon, November 16th.
All money raised goes towards
research into the generic drug, DCA, being conducted at the
University of Alberta.
Congratulations and many thanks to
Julie
Gagnon who made the top bid on the Digging of a
Basement.
TOP
BID #1: $
1,250
Congratulations
and many thanks to
Karen Stephens who made the top
bid on the Electrical Services.
TOP BID #2: $
550
Congratulations
and many thanks to
Jack Hanson who made the
top bid on the safety package.
TOP BID #1: $
650
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Q:
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How
did the DCAuction on the Signature Washburn Guitar turn out?
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A: |
IT'S A
COLLECTABLE WASHBURN SIGNATURE GUITAR !!!
This SIGNATURE GUITAR is donated by CUSTOM COMPUTERS & MUSIC in Peace
River and has been autographed
by your favourite artists from TELUS
COUNTRY FEVER and PEACEFEST.
All your favourites like...
PRISM,
NAZARETH, EMERSON DRIVE, THE POVERTY PLAINSMEN, THE WILKINSONS, THE HEADPINS, DARRYL WORLEY, DARBY MILLS, JULIE ROBERTS, LORRIE MORGAN and MORE...
Bidding closed at
noon on November 30th. All money raised goes
towards DCA research.
Congratulations to Ron at Falher IDA who made the highest bid of
$1,000.
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DCAuction
IT'S A
COLLECTABLE WASHBURN SIGNATURE GUITAR !!!
This
SIGNATURE GUITAR is
donated by CUSTOM COMPUTERS &
MUSIC in Peace River and has been autographed by your favourite
artists from TELUS COUNTRY
FEVER and PEACEFEST.
All your
favourites like...
PRISM, NAZARETH, EMERSON DRIVE, THE POVERTY PLAINSMEN, THE WILKINSONS, THE HEADPINS, DARRYL WORLEY, DARBY MILLS, JULIE ROBERTS, LORRIE MORGAN and MORE...
Bidding closed at
Noon, November 30th.
All
money raised goes towards research into the generic drug, DCA,
being conducted at the University of Alberta.
Congratulations
and many thanks to
Ron at Falher IDA who made the top bid
on the Signature Washburn Guitar.
TOP BID:
$
1000
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Q:
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How is the
fundraising going?
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A: |
We are striving to raise a total of $250,000
to help in the research that they are doing at the University of
Alberta toward determining with absolute certainty that DCA is
effective and safe in patients with cancer. Studies involving
thousands of patients with different cancers, from different
hospitals and different countries have to be conducted. Often,
direct comparisons of one experimental treatment with other standard
therapies are required. These large-scale trials will take years to
complete and will require hundreds of millions of dollars.
In order to see how
close we are to our goal of $250,000 toward what may be an
affordable and successful means of battling a terrible desease, we
will keep a running total posted on this website.
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DCA
Fundraising Running Total
The ultimate fundraising
goal is $1,000,000 with $250,000
coming from the Peace Region .
The closer we
come to attaining our goal of raising $250,000 to aid in the
DCA research being done at the University of Alberta by Doctor
Michelakis and his team, the closer we come to seeing a
possible new hope for many cancer sufferers.
We have exceeded our original goal and
raised a total of $325,000 !!!!
Thank you to everyone for being part of
this effort.
CLICK HERE TO PRINT A DONATION FORM
(Adobe
Acrobat PDF) | |
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Q:
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I missed Mody's
interview with Doctor Michelakis. Is there any way I can listen to
it?
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A: |
YL Country's Dan Mody, had the
pleasure of a conversation with Doctor Michelakis, who is heading up
the DCA research team at the University of Alberta. This interview
aired on KIX and YL Country on Tuesday, April 17th, 2007. If you
missed it, or would like to hear it again, you can listen to it
here.
This
interview entitled "DCA - The Grassroots Fight Against Cancer" has
been split into 4 sections for your listening convenience.
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Q:
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I missed Mody's
most recent interview with Doctor Michelakis. Is there any way I can
listen to it?
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A: |
YL Country's Dan Mody, had the
pleasure of a follow-up conversation with Doctor Michelakis, who is
heading up the DCA research team at the University of Alberta. This
interview aired mid-September, 2007, on YL Country. If you missed
it, or would like to hear it again, you can listen to it here.
This interview has
been split into 2 sections for your listening convenience.
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Q:
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What is DCA and
how does it work?
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A: |
DCA is a drug that “boosts” the function of
mitochondria. Mitochondria are the energy-producing units within
cells and they regulate the energy production in the body (i.e. the
metabolism). Cancer somehow suppresses the function of mitochondria
and by achieving this it gains “eternal life”. We believe that
cancer cells die when the mitochondria are “normalized” or boosted
by DCA. Because these effects in mitochondria occur only in cancer
and not normal cells, we believe that DCA will not have the
significant side effects (hair loss, nausea, heart failure etc) that
many standard chemotherapies have.
Basically, DCA reactivates the
energy-producing organelles of cells (mitochondria), and allows the
cancerous cells to commit suicide (apoptosis).
Here's what happens...
Many types of cancer
cells shut down the cell's mitochondria, the primary energy
producing parts of a cell. By doing so, the cancer cell also shuts
down the cell suicide mechanism, known as apoptosis, which is
initiated by the mitochondria. The research team of Doctors
Michelakis and Archer of the University of Alberta found that DCA
opens up the ‘channels’ on the membrane of those mitochondria,
essentially waking them up. The functioning mitochondria can then
initiate the suicide process.
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Q:
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Can my doctor
order DCA?
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A: |
Your doctor cannot prescribe DCA since it is
currently not approved for use in patients with cancer. DCA is not
available in pharmacies. The only way that DCA will become available
for use in patients with cancer is under appropriately performed
clinical trials and supervision by appropriate regulatory agencies
like Health Canada or the Food and Drug Administration in the
USA.
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Q:
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Can I find and
use DCA on my own?
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A: |
Absolutely not! This can actually be
dangerous. For example, DCA can be found in stores selling chemicals
to scientific laboratories. Often, DCA is sold in a form that is
very acidic and if consumed could cause serious or catastrophic
complications. Even for use in animals DCA often has to be processed
with chemicals to correct its acidity etc. In addition, the dose in
patients with cancer, or its interactions with other medications
that cancer patients might be on, are completely unknown.
Often, patients with
terminal cancer might feel they are in a desperate situation and
might be “willing to try anything”. It needs to be remembered that
the inappropriate use of these drugs might cause catastrophic
complications and make the situation even worse. In addition, if
complications occur, because this was not done under the supervision
of a physician, this problem will not become known and other
patients might be exposed to a risk that could have been prevented.
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Q:
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Can DCA treat
my cancer?
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A: |
DCA was shown to have beneficial effects in
lung and breast cancer as well as a form of brain cancer
(glioblastoma). These effects occurred in human cancers growing in
the test tube. In the case of lung cancer, tumors growing in rats
decreased in size after the rats were given DCA. The effects on
other kinds of tumors are completely unknown. However, because
mitochondria appear to be suppressed in many different forms of
cancer, we speculate that DCA will have beneficial effects in other
types of cancer as well. Once again, in order to determine if DCA is
effective (and safe) in patients with cancer, appropriately
conducted clinical trials are absolutely required.
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Q:
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When will the
clinical trials start?
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A: |
In order to be absolutely certain that DCA
is effective and safe in patients with cancer, studies involving
thousands of patients with different cancers, from different
hospitals and different countries have to be conducted. Often,
direct comparisons of one experimental treatment with other standard
therapies are required. These large-scale trials will take years to
complete and will require hundreds of millions of dollars.
However, smaller and
more focused trials can occur much faster. The funding required for
such trials is less (in the range of hundreds of thousands of
dollars) and the procedures are easier than in drugs that have never
before tried in any human being. Still, protocols of such trials
need to be approved by local and federal agencies and funding
secured.
A number
of physicians and scientists from the University of Alberta and the
Alberta Cancer Board have already started working together and have
received commitment from the leadership of these institutions to
help make these trials happen as soon as possible. We hope that
initiation of trials will occur shortly, i.e. within a few months.
We plan to post our progress towards this goal on this website.
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Q:
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How can I
help?
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A: |
We appreciate your interest and support, and
we have been touched by your kind words. We also understand the
agony in many of you that you see your loved ones in desperate need
of a treatment or a hope. We have been working on this for at least
2 years now and we will continue to work hard in order to determine
whether this drug can actually benefit human beings with cancer.
Your continued support of research in general is greatly appreciated
by all of us in this field and it is important since a great deal of
funding comes directly from the people (tax payer money coming to us
through federal funding agencies like CIHR or charities). If you
want to directly support this effort (that at this time receives no
financial support from “for profit” organizations, pharmaceutical or
private companies), you can do so in this web site.
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Q:
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How can I make
a donation?
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A: |
We appreciate your interest and support, and
we have been touched by your kind words. If you want to directly
support this effort (that at this time receives no financial support
from “for profit” organizations, pharmaceutical or private
companies), you can do so by clicking one of the links below or by
visiting the Official University of Alberta DCA Website
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DONATIONS |
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Donations can be mailed or dropped off
at:
Faculty of Medicine & Dentistry
Room 2J1
Walter C Mackenzie Health Sciences
Centre
University of Alberta
Edmonton, Canada T6G 2R7
Please note on your cheques that you
would like your donations to support Dr. Michelakis’ cancer
research.
If you would like to speak to someone
about making a gift
please contact:
Holli Bjerland,
Sr. Development Officer
University of Alberta, Department of
Medicine
2F1.26 Walter C Mackenzie
Health Sciences Centre
Edmonton, AB
CANADA T5G 2R7
Fax: (780) 407-3340
E-mail: holli.bjerland@ualberta.ca
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Everything in the above dark-blue square
is identical to the information found on the
Official
University of Alberta DCA Website .
Donation links
will open documents or forms which reside on that
site.
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